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Hrishikesh Pai: Role of Vaginal and Gut Microbiota in HPV Progression and Cervical Cancer
Hrishikesh Pai/LinkedIn
Jun 8, 2026, 10:40

Hrishikesh Pai: Role of Vaginal and Gut Microbiota in HPV Progression and Cervical Cancer

Hrishikesh Pai, Founder and Managing Director at Bloom IVF India, shared a post on LinkedIn:

”Delighted to share that our team’s latest research has been published in Cureus — a PubMed-indexed peer-reviewed journal!

‘Role of Vaginal and Gut Microbiota in Human Papillomavirus (HPV) Progression and Cervical Cancer: A Systematic Review of Microbial Diversity and Probiotic Interventions’
Cureus. 2025 Jun 12;17(6):e85880
DOI: 10.7759/cureus.85880

Cervical cancer remains one of the leading causes of cancer mortality in women globally. This systematic review — analysing 82 published studies — explores a critical emerging question: how do the vaginal and gut microbiome influence HPV infection, its progression to cervical intraepithelial neoplasia (CIN), and cervical cancer?

Key highlights:

  • Microbial dysbiosis plays a significant role in HPV progression and clearance
  • The gut-cervical microbiome axis is an important and underexplored pathway
  • Probiotics show promising therapeutic and preventive potential
  • Conducted per PRISMA guidelines | PROSPERO registered (#CRD42024584685)
  • Published in Cureus — indexed on PubMed/MEDLINE

This work opens new frontiers in cervical cancer prevention — beyond vaccination and screening, towards microbiome-based strategies.

Proud to have collaborated with an exceptional team:
Dr. Rashmi Baid | Dr. Nandita P Palshetkar | Dr. Rishma Pai | Dr. Arnav Pai | Dr. Rohan Palshetkar

Full paper on PubMed.”

Title: Role of Vaginal and Gut Microbiota in Human Papillomavirus (HPV) Progression and Cervical Cancer: A Systematic Review of Microbial Diversity and Probiotic Interventions

Authors: Hrishikesh D. Pai, Rashmi Baid, Nandita P. Palshetkar, Rishma Pai, Arnav Pai, Rohan Palshetkar

Role of Vaginal and Gut Microbiota in Human Papillomavirus (HPV) Progression and Cervical Cancer

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Bloom IVF Cervical cancer Fertility Fertility and Sterility Fertility News Hrishikesh Pai Human Papillomavirus (HPV) infertility IVF Microbial Dysbiosis OBGYN pregnancy PubMed reproductive health Reproductive Medicine Women’s Health
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