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The Mystery of Unexplained Infertility, A Hidden Barrier Revealed! – Fertility Plus
Jul 1, 2026, 10:01

The Mystery of Unexplained Infertility, A Hidden Barrier Revealed! – Fertility Plus

Fertility Plus shared a post on LinkedIn:

“The Mystery of ‘Unexplained’ Infertility: A Hidden Barrier Revealed!

Many couples face the heart-wrenching challenge of infertility, only to be told that everything looks normal. But what if there’s a hidden factor at play?

Research shows that between 5-12% of men may have antisperm antibodies that their immune system mistakenly creates against their own sperm. These antibodies can elevate oxidative stress and DNA fragmentation, preventing sperm from successfully fertilizing an egg.

The good news? A single blood test—the MAR test—can reveal the percentage of sperm affected by these antibodies. This crucial information leads directly to effective treatments like ICSI, significantly increasing fertilization and live birth rates.

Don’t let ‘unexplained’ infertility remain a mystery! There is hope and a solution waiting to be uncovered.
Lindenbaum MM, Kuribayashi S, Lundy SD. Antisperm antibodies and autoimmunity in the era of assisted reproduction. Fertility and Sterility 2026.”

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