DIVINE Calculator Makes IVF Dosing Safer Without Reducing Effectiveness – RBMO
Reproductive BioMedicine Online (RBMO) shared a post on LinkedIn:
“The DIVINE dose calculator uses easily obtainable patient characteristics to provide clinicians with multiple possible starting doses, each with estimated safety risks and expected live birth implications
This new study from Nienke Schouten, Theodora van Tilborg, Daniela Cianci, Marinus Eijkemans, Marieke Lambers, and Frank J.M. Broekmans investigates the use of this calculator in routine care, and its influence on reducing treatment risk due to ovarian hyperstimulation.
The authors found that implementing the calculator for FSH dose picking in routine IVF/ICSI care resulted in a more safe and equally effective approach in first, fresh IVF/ICSI cycles.
While standard dosing may result in similar live birth rates, individualised dosing can lead to fewer adverse events due to an excessive ovarian response and will be a valuable part of the preventative management of OHSS for predicted high responders.
While more research is needed to fully evaluate the benefits of implementing the DIVINE dose calculator, the results in this paper indicate its promising potential as a tool for optimisation of fertility care.
The paper is published open access, available to read in full from our in-press articles section, now.”
Title: The DIVINE dose-selection model in daily ART practice: effects on live birth rate and safety
Authors: Nienke Schouten, Theodora van Tilborg, Daniela Cianci, Marinus Eijkemans, Marieke Lambers, and Frank J.M. Broekmans
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
May 24, 2026, 19:45Danielle Uses Her Voice and Story to Help Create Change – Preeclampsia Foundation
-
May 24, 2026, 19:42Jakub Dejewski: Looking Back at The Fertility Show at Olympia London
-
May 24, 2026, 09:50Sima Alnamoora: Day 5 Early Hatching Blastocyst Captured During IVF Cycle Monitoring
-
May 24, 2026, 07:29Lucile Ferreux: The Hidden Reality of Male Fertility, Have You Ever Had a Spermiogram?
-
May 24, 2026, 07:25Cesar Fertility Newsletter Highlights Lifestyle Impact on Male Fertility Awareness – Cesar Fertility
-
May 24, 2026, 07:21Carla Wicks: Understanding Racial Differences in Endometriosis Care Pathways
-
May 24, 2026, 07:14Why Do French Men Go 20 to 30 Years Without Any Genital Examination? – Cesar Fertility
-
May 24, 2026, 07:11Lucile Ferreux: Sperm Racing Event Sparks Debate on Male Fertility Awareness and Scientific Accuracy
-
May 24, 2026, 07:08Unlocking the Black Box of Implantation Failure with Multi-Dimensional AI in IVF – Santaan Fertility Center and Research Institute