Have You Ever Wondered Why a Man With Perfect Semen Analysis Still Struggles to Conceive? – Fertility Plus
Fertility Plus shared a post on LinkedIn:
“Have you ever wondered why a man with perfect semen analysis still struggles to conceive?
A groundbreaking study published in 2026 reveals that invisible inflammation in the male reproductive tract might be the missing piece of the infertility puzzle!
Even if sperm count, motility, and morphology are all normal, elevated inflammatory proteins called cytokines can lurk in seminal plasma, potentially affecting fertility without being detected in standard tests.
Research highlights three key cytokines: IL-6, TNF-α, and CXCL8, which are linked to inflammation and immune activation. This hidden inflammation could be a significant factor contributing to infertility.
As we strive for better understanding and solutions, it’s essential to consider additional testing like cytokine analysis for a more comprehensive evaluation. The WHO now recommends this as part of extended semen evaluation!
Human Reproduction Update in 2026 — Lyons et al.,
Let’s raise awareness about male infertility and the importance of looking beyond the standard tests. Together, we can support couples on their journey to parenthood!.”

Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Oct 28, 2026, 15:55Katy Encalade: What Are the Biggest Myths About Egg Donation?
-
Oct 28, 2026, 15:53Diana Kayal: A Free Webinar on Trauma, Infertility and the Patient Journey
-
Oct 28, 2026, 15:49Rebecca Watson O’Connor: Applications for the 2027 PRIMED Cohort Are Open
-
Oct 28, 2026, 15:45Martin Varsavsky: Gameto Has Been Acquired by Ferring for 1.38 Billion Dollars
-
Oct 28, 2026, 15:37Gili Band: The People Are What Stay With Me After Day 1 at ASRM 2026
-
Oct 28, 2026, 13:56Samantha Payne: NSW Releases Final Report on Fertility Support and Assisted Reproductive Treatment
-
Oct 28, 2026, 13:53True Friendship and PCOS: Why Emotional Support Matters – PCOS Millennials
-
Oct 28, 2026, 13:51Fred Ushakov: The Future of Prenatal Screening, The Future of Your Practice
-
Oct 28, 2026, 13:49Hosting the First-Ever Fairfax Awards – Fairfax EggBank
