Hrishikesh Pai: Role of Vaginal and Gut Microbiota in HPV Progression and Cervical Cancer
Hrishikesh Pai, Founder and Managing Director at Bloom IVF India, shared a post on LinkedIn:
”Delighted to share that our team’s latest research has been published in Cureus — a PubMed-indexed peer-reviewed journal!
‘Role of Vaginal and Gut Microbiota in Human Papillomavirus (HPV) Progression and Cervical Cancer: A Systematic Review of Microbial Diversity and Probiotic Interventions’
Cureus. 2025 Jun 12;17(6):e85880
DOI: 10.7759/cureus.85880
Cervical cancer remains one of the leading causes of cancer mortality in women globally. This systematic review — analysing 82 published studies — explores a critical emerging question: how do the vaginal and gut microbiome influence HPV infection, its progression to cervical intraepithelial neoplasia (CIN), and cervical cancer?
Key highlights:
- Microbial dysbiosis plays a significant role in HPV progression and clearance
- The gut-cervical microbiome axis is an important and underexplored pathway
- Probiotics show promising therapeutic and preventive potential
- Conducted per PRISMA guidelines | PROSPERO registered (#CRD42024584685)
- Published in Cureus — indexed on PubMed/MEDLINE
This work opens new frontiers in cervical cancer prevention — beyond vaccination and screening, towards microbiome-based strategies.
Proud to have collaborated with an exceptional team:
Dr. Rashmi Baid | Dr. Nandita P Palshetkar | Dr. Rishma Pai | Dr. Arnav Pai | Dr. Rohan Palshetkar
Full paper on PubMed.”
Title: Role of Vaginal and Gut Microbiota in Human Papillomavirus (HPV) Progression and Cervical Cancer: A Systematic Review of Microbial Diversity and Probiotic Interventions
Authors: Hrishikesh D. Pai, Rashmi Baid, Nandita P. Palshetkar, Rishma Pai, Arnav Pai, Rohan Palshetkar
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