Yanhe Liu: How Refinements in PGT Laboratory Procedures May Influence Clinical Outcomes
Yanhe Liu, National Scientific Director at City Fertility and Clinical Associate Professor at The University of Western Australia, shared a post on LinkedIn about a paper he co-authored with colleagues published in Reproductive Biomedicine Online:
“New publication – Optimising PGT laboratory practice
Following our previous meta-analysis on the impact of double biopsy and double vitrification on euploid embryo transfer outcomes in Human Reproduction 2024, we continue to explore how refinements in PGT laboratory procedures may influence clinical outcomes.
Our newly published systematic review and meta-analysis in Reproductive BioMedicine Online examines another important question: day 5/6 sequential hatching and biopsy versus day 3 artificial hatching.
Our findings suggest potential improvements in clinical pregnancy and live birth rates with day 5/6 sequential hatching/biopsy, alongside increased reporting of mosaicism and no PGT result.
Together, these studies highlight the importance of critically evaluating every step of the PGT workflow, balancing laboratory practice, genetic reporting and clinical outcomes.”
Title: Day 5/6 sequential hatching/biopsy versus day 3 hatching before blastocyst biopsy: systematic review and meta-analysis.
Authors: Yanhe Liu, Fang Qi, Roger Hart.
You can read the Full Article in Reproductive BioMedicine Online.
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Oct 12, 2026, 16:55Karthik Raj: True Biological Embryo Mosaicism vs. Technical Detection
-
Oct 12, 2026, 16:50Nagi Rostom: Sharing Insights on Reproductive Health and Fertility at a Women’s Health Open Morning
-
Oct 12, 2026, 16:44Katy Encalade: Why Early Education Matters in Egg Donation and Surrogacy
-
Oct 12, 2026, 16:31It’s Time to Talk about Fertility-Aware Workplaces – ESHRE
-
Oct 12, 2026, 16:23Anu Chawla: WHO’s Global Roadmap for Hypertensive Disorders of Pregnancy Is a Significant Step Forward
-
Oct 12, 2026, 16:11Devyanshi Dixit: Behind Every Breakthrough Is a Reason to Keep Going
-
Oct 12, 2026, 16:01Suganya Venkat: The Kindest Thing to Say After a Failed IVF Cycle Is Not “Try Again”
-
Oct 12, 2026, 15:58Lucy Froese: When You Lose a Pregnancy, You Don’t Just Lose Your Baby…
-
Oct 12, 2026, 15:56Beata Blazkova: What Actually Makes an Embryo Keep Going?