Kenji Ezoe: Can Prolactin Improve Embyo Transfer Outcomes?
Kenji Ezoe, Senior Scientist at Kato Ladies Clinic, shared a post on LinkedIn:
“New Publication
Can prolactin improve embryo transfer outcomes?
Our randomized controlled trial, recently published in Reproductive BioMedicine Online, explored the effect of combining prolactin (PRL) with a hyaluronic-acid–enriched transfer medium (EmbryoGlue) for single vitrified-warmed blastocyst transfer (SVBT).
In a double-blind RCT of 1,236 couples, the EGP group (EmbryoGlue + PRL) showed:
- Higher live birth rate
- Higher ongoing pregnancy rate
- Lower early pregnancy loss
compared with both the control and EmbryoGlue groups, with no increase in adverse outcomes.
These findings suggest that PRL supplementation during embryo transfer may help improve live birth outcomes by reducing early pregnancy loss.
Title: Post-warming culture and single vitrified-warmed blastocyst transfer with hyaluronic acid and prolactin: a randomized controlled trial
Authors: Kenji Ezoe, Tetsuya Miki, Nanoha Fujiwara, Satoshi Ueno, Mika Narisawa, Kiyoe Shimazaki, Ryosuke Akino, Shogo Nishii, Sachie Onogi, Satoshi Tsuchiyama, Keiko Wada, Tomoko Kuroda, David K. Gardner, Keiichi Kato
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
May 25, 2026, 00:14Fabio Castiglione: Pleased and Honoured to Be Working Alongside Outstanding Professionals
-
May 25, 2026, 00:09First-trimester Prediction and Prevention of Preterm Pre-eclampsia – ISUOG
-
May 25, 2026, 00:07Awais Hamza: Ultrasound Clues Every Sonographer Should Recognize for Patau Syndrome
-
May 24, 2026, 19:45Danielle Uses Her Voice and Story to Help Create Change – Preeclampsia Foundation
-
May 24, 2026, 19:42Jakub Dejewski: Looking Back at The Fertility Show at Olympia London
-
May 24, 2026, 09:50Sima Alnamoora: Day 5 Early Hatching Blastocyst Captured During IVF Cycle Monitoring
-
May 24, 2026, 07:29Lucile Ferreux: The Hidden Reality of Male Fertility, Have You Ever Had a Spermiogram?
-
May 24, 2026, 07:25Cesar Fertility Newsletter Highlights Lifestyle Impact on Male Fertility Awareness – Cesar Fertility
-
May 24, 2026, 07:21Carla Wicks: Understanding Racial Differences in Endometriosis Care Pathways