DIVINE Calculator Makes IVF Dosing Safer Without Reducing Effectiveness – RBMO
Reproductive BioMedicine Online (RBMO) shared a post on LinkedIn:
“The DIVINE dose calculator uses easily obtainable patient characteristics to provide clinicians with multiple possible starting doses, each with estimated safety risks and expected live birth implications
This new study from Nienke Schouten, Theodora van Tilborg, Daniela Cianci, Marinus Eijkemans, Marieke Lambers, and Frank J.M. Broekmans investigates the use of this calculator in routine care, and its influence on reducing treatment risk due to ovarian hyperstimulation.
The authors found that implementing the calculator for FSH dose picking in routine IVF/ICSI care resulted in a more safe and equally effective approach in first, fresh IVF/ICSI cycles.
While standard dosing may result in similar live birth rates, individualised dosing can lead to fewer adverse events due to an excessive ovarian response and will be a valuable part of the preventative management of OHSS for predicted high responders.
While more research is needed to fully evaluate the benefits of implementing the DIVINE dose calculator, the results in this paper indicate its promising potential as a tool for optimisation of fertility care.
The paper is published open access, available to read in full from our in-press articles section, now.”
Title: The DIVINE dose-selection model in daily ART practice: effects on live birth rate and safety
Authors: Nienke Schouten, Theodora van Tilborg, Daniela Cianci, Marinus Eijkemans, Marieke Lambers, and Frank J.M. Broekmans
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Jul 10, 2026, 15:37Paola Fasola: The Value of Time: Reflections from ESHRE 2026
-
Jul 10, 2026, 15:05Marco Zaccaria: Masterclass Organized by MSEC On The Basics of Hysteroscopy
-
Jul 10, 2026, 14:50The Prevention of Group B Streptococcal Disease in Perinatal Period – RCOG
-
Jul 10, 2026, 14:24Christopher Robinson: Myometrial Marking to Improve Suturing of the Uterine Incision at Cesarean Delivery
-
Jul 10, 2026, 13:28Emad Sedeek: PGT-A Is a Diagnostic Tool, Not a Guaranteed Pathway to Higher IVF Success
-
Jul 10, 2026, 13:10Nimra Zulfiqar: RCT Finds Dinoprostone–Laminaria Combination Reduces Cesarean Deliveries During Labor Induction
-
Jul 9, 2026, 18:08Camille A. Clare and Willie Underwood Ill Highlight Coding Changes for Every Stage of Pregnancy – ACOG
-
Jul 9, 2026, 15:53Practical Advice to Help Pregnant Women Stay Safe During Periods of Extreme Heat – FIGO
-
Jul 9, 2026, 15:42Serum Estradiol Decline Before Ovulatory Trigger and ART Outcomes – Fertility and Sterility