Sergio Haimovich: Endometrial Pathophysiology and Pregnancy, From Mechanism to Intervention!
Sergio Haimovich, Director for Europe, Middle East and Africa at the AAGL Board of Directors, shared a post on LinkedIn:
“NEW HYSTERO360 EPISODE Global Community of Hysteroscopy
Endometrial Pathophysiology and Pregnancy: From Mechanism to Intervention
Why can an apparently normal endometrium still fail to support a pregnancy?
In this new episode, we explore the complex interaction between immunity, inflammation, metabolism, epigenetics, and endometrial function.
We examine how chronic inflammation, immune-cell dysfunction, and epigenetic changes may impair implantation and contribute to reproductive failure in conditions such as:
- Endometriosis
- Intrauterine adhesions
- Endometrial immune dysfunction
- Impaired tissue regeneration
But the future goes beyond diagnosis. We also discuss emerging approaches such as stem-cell bioengineering, epigenetic reprogramming, and targeted interventions designed to restore endometrial receptivity and fertility.
From biological mechanisms to clinical intervention.
Listen now to the latest episode of Hystero360, the podcast of the Global Community of Hysteroscopy — GCH.
Diao L, Kwak-Kim J. Endometrial pathophysiology and pregnancy: from mechanism to intervention. Semin Immunopathol. 2026 May 19;48(1):8. doi: 10.1007/s00281-026-01074-z. PMID: 42156567.”
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