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Marco Zaccaria: Link Between Vaginal Microbiota and Uterine Fibroids Explored
Marco Zaccaria/LinkedIn
Feb 23, 2026, 16:46

Marco Zaccaria: Link Between Vaginal Microbiota and Uterine Fibroids Explored

Marco Zaccaria, Global Product Manager at H.S. Hospital Service SpA, shared a post on LinkedIn about a paper by Xuetao Mao et al. published in Frontiers in Cellular and Infection Microbiology:

“Recent scientific research is highlighting a significant correlation between the state of the vaginal microbiota and the development of uterinefibroids.

Women with uterine fibroids often have an alteration in their vaginal bacterial flora, in particular a lower concentration of protective lactobacilli compared to healthy women

There is a close link between the vaginal microbiota and hormone metabolism: some bacteria produce the enzyme beta-glucuronidase, which reactivates estrogens destined for excretion, putting them back into circulation. Since fibroids are hormone-dependent tumors, an excess of circulating estrogens promotes their growth

The integration of specific lactobacilli can help restore the balance of the flora and improve the health of the endometrium.

For further information, read this interesting article. Enjoy!”

Title: Dysbiosis of vaginal and cervical microbiome is associated with uterine fibroids

Article: Xuetao Mao, Hao Chen, Xuan Peng, Xingping Zhao, Zheng Yu, Dabao Xu

Marco Zaccaria

Stay updated on all scientific advances in the field of fertility with Fertility News.

Bacterial Diversity Bacterial Flora Dabao Xu Estrogen Regulation Fertility Fertility News Fibroid Development Gynecological Research Hao Chen Hormonal Balance Hormone Metabolism Lactobacilli Levels Marco Zaccaria Microbial Influence Microbiome Research Uterine Fibroids Vaginal Microbiota Xingping Zhao Xuan Peng Xuetao Mao Zheng Yu
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