New Lancet Studies Question the Evidence Behind Common IVF Add-Ons – The Lancet Group
The Lancet Group shared a post on LinkedIn:
“Many IVF add-ons are marketed with the promise of improving treatment success. But what does the evidence show?
A new study reviewed 10 common IVF add-ons and found that most have not been proven to improve IVF outcomes — Evidence is often limited, uncertain, or of low quality.
‘IVF clinics and clinicians should carefully consider whether it is appropriate to offer unproven add-ons, as their availability is often perceived by patients as implicit endorsement of benefit’ — Dr Sarah Lensen, Lead author.
To address the widespread availability of poor-quality information, Dr Sarah Lensen and her team developed the Evidence-based IVF website. A second study found that the website improved patients’ understanding of the benefits, risks, and evidence quality of IVF add-ons.
Read more in The Lancet Obstetrics, Gynaecology, and Women’s Health
Paper 2.”
Title: Safety and effectiveness of ten common in-vitro fertilisation add-ons: a systematic review and meta-analysis
Authors: Sarah Lensen, Jack Wilkinson, Michelle Steeper, Pedro Melo, Mohan S Kamath, Laurentiu Craciunas, Rui Wang, Vanessa Jordan, Marian Showell, Sara Attinger, Afsana Afroz, Madelon van Wely, Cynthia Farquhar

Title: Evaluation of a codesigned resource about in-vitro fertilisation add-ons: an online, parallel-group, single-blinded, randomised trial
Authors: Afsana Afroz, Hilary Smith, Tessa Copp, Deanna De Ciccob, Jack Wilkinson, Eleni Roumian, Michael Costello, Genia Rozen, Michelle Peate, Prof Tammy Hoffmann, Sarah Lensen

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