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Andrea Etrusco: Rethinking Hormone Add-Ons for Poor Ovarian Response

Andrea Etrusco/LinkedIn

Oct 29, 2025, 07:32

Andrea Etrusco: Rethinking Hormone Add-Ons for Poor Ovarian Response

Andrea Etrusco, Reproductive Medicine Fellow at Cliniques universitaires Saint-Luc, shared a post on LinkedIn about a paper published in the Journal of Assisted Reproduction and Genetics:

“Hormone add-on strategies in poor ovarian response: which one really works?

In our new paper published in the Journal of Assisted Reproduction and Genetics, we conducted a systematic review and network meta-analysis of 22 randomized controlled trials including more than 4100 women with poor ovarian response (POR, Bologna criteria).

No single add-on can yet be recommended as standard, and that decisions should be individualized, balancing biological plausibility, patient characteristics, and cost-effectiveness.

What we truly need are well-designed, high-quality RCTs to clarify which patients, if any, might benefit from specific interventions.”

Title: Effectiveness of hormone add-on strategies in ovarian stimulation for women with poor ovarian response: a systematic review and network meta-analysis of randomized controlled trials

Authors: Andrea Etrusco, Vittorio Agrifoglio, Juan Carlos Castillo Farfán, Andrea Bernabeu Garcia, Antonio Simone Laganà, Belén Moliner Renau, Antonio D’Amato, Pasquale De Franciscis, Ana Fuentes Rozalén, Gaetano Riemma

Read the full article.

Andrea Etrusco