Key Discoveries in Embryo Implantation Mechanisms Unveiled – ICMR NIRRCH
ICMR – National Institute for Research in Reproductive and Child Health (NIRRCH) shared a post on LinkedIn about a paper by Nancy Ashary et al. published in Nature:
“Implantation of the embryo in to the mother’s uterus is key to initiate pregnancy and IVF success.
Our scientists determined the mechanism of this process. They discovered that two genes (HOXA1O and TWIST2) work in oposition to control the process called as EMT in the uterus at the site where the embryo attaches. Inhibiting EMT leads to implantation and pregnancy failure.
This study was published in the international journal Cell Death Discovery
It was a collaboration with IISc Banglore and and BHU Varanasi.
Read full text here.”
Title: HOXA10-TWIST2 antagonism drives partial epithelial-to-mesenchymal transition for embryo implantation
Authors: Nancy Ashary, Sanjana Suresh, Anshul Bhide, Sharmishtha Shyamal, Pranya N, Saee Patil, Anuradha Mishra, Anuradha A, Shruti R. Hansda, Harshavardhan BV, Mohit Kumar Jolly, Deepak Modi
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
May 6, 2026, 01:35Alison Wright: BSGE 2026 Highlights Leadership Change and Future Vision
-
May 6, 2026, 01:30Short Menstrual Cycles May Signal Early Ovarian Ageing – Fertility Plus
-
May 6, 2026, 01:27Asma Khalil: Maternal Mental Health Remains a Leading Risk
-
May 5, 2026, 16:55Pregnancy Outcomes in a Recurrent Miscarriage Population After Uterine Surgeries – Fertility and Sterility
-
May 5, 2026, 16:43MAGENTA Oocyte Scores, Morphokinetics and Live Birth – Future Fertility
-
May 5, 2026, 16:34Join Us on 16 September to Explore Challenges in Managing a Successful Fertility Service – BFS
-
May 5, 2026, 16:17Mature Oocyte Retrieval Without an Exogenous Trigger During Stimulation – Fertility and Sterility
-
May 5, 2026, 16:08We Are Delighted to Announce that Fertility 2027 Registration Opens soon – Fertility Conferences
-
May 5, 2026, 15:59Lillian’s Story Highlights Urgency of Recognising Postpartum Preeclampsia – Preeclampsia Foundation