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2025 Medicine Awarded for Discoveries in Immune System Regulation – The Nobel Prize
The Nobel Prize/LinkedIn
Oct 12, 2025, 07:46

2025 Medicine Awarded for Discoveries in Immune System Regulation – The Nobel Prize

The Nobel Prize shared a post on LinkedIn:

“BREAKING NEWS
The Nobel Assembly at Karolinska Institutet has decided to award the 2025 Nobel Prize in Physiology or Medicine to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi ‘for their discoveries concerning peripheral immune tolerance.’

This year’s medicine laureates have discovered how the immune system is kept in check. The body’s powerful immune system must be regulated, or it may attack our own organs. Brunkow, Ramsdell and Sakaguchi have been awarded this year’s medicine prize for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.

The laureates identified the immune system’s security guards, regulatory T cells, which prevent immune cells from attacking our own body.

The laureates’ discoveries launched the field of peripheral tolerance, spurring the development of medical treatments for cancer and autoimmune diseases. This may also lead to more successful transplantations. Several of these treatments are now undergoing clinical trials.

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Yann Bouvet, Sr Director of manufacturing and partnerships at GE Health Care, shared The Nobel Prize’s post, adding:

“Identification of regulatory T cells and FOXP3 , Nobel prize winning project for the 2025 Nobel prize in physiology or Medicine”

2025 Nobel prize in physiology or Medicine Fertility Fertility News FOXP3 Fred Ramsdell Karolinska Institutet Mary E. Brunkow Nobel Prize peripheral immune tolerance regulatory T cells Shimon Sakaguchi Yann Bouvet
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