HCG and GnRH Analogue Trigger Failure – Fertility Plus
Fertility Plus shared a post on LinkedIn:
“HCG and GnRH analogue trigger failure
A recent large retrospective analysis has shed light on the effectiveness of different trigger types in IVF cycles. Comparing 2,034 donor GnRHa-trigger cycles with 1,433 hCG-trigger cycles, the study found EFS incidences of 3.5% for GnRHa and 3.1% for hCG, indicating no significant difference between the two methods when executed properly. This aligns with earlier literature citing a 2–7% EFS incidence for hCG triggers, reinforcing that trigger type alone does not appear to increase EFS risk.
J Assist Reprod Genet (2012) 29:249–253
DOI 10.1007/s10815-011-9704-8
Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS Juan C. Castillo and Juan Garcia-Velasco and Peter Humaidan IVF.”
Title: Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS
Author: Juan C Castillo, Juan Garcia-Velasco, Peter Humaidan
Read the full article.

-
Sep 15, 2026, 18:18A PCOS Diagnosis Can Stay in the Background of Every Fertility Conversation – Banker IVF and Women’s Hospital
-
Sep 15, 2026, 18:15The Difference Between Ovulation Induction and Ovarian Stimulation – Fertility Plus
-
Sep 15, 2026, 18:13Ritu Anand: What Would I Tell an IVF Couple in the 1980s?
-
Sep 15, 2026, 18:11STP Curriculum Feedback Survey – The Association of Reproductive and Clinical Scientists
-
Sep 15, 2026, 18:09Khushi Mishra: ICSI – Where Precision Meets the Possibility of Life
-
Sep 15, 2026, 18:06Khalil Faaed: The Future of niPGT-A Is Not Just Non-Invasive…
-
Sep 15, 2026, 18:04Anuradha Housnur: ICSI Is Not About Injecting the Sperm…
-
Sep 15, 2026, 18:02Snehal Kaware: Can an Oocyte With a Vacuole Still Fertilize?
-
Sep 15, 2026, 17:59Kanishka Gaur: Amenorrhea Is a Symptom, Not a Diagnosis
