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ASCO26 Research Flags Elevated Maternal Mortality Risk in Pregnant Women With Myeloproliferative Neoplasms – Hematology Advisor
Hematology Advisor/LinkedIn
Jun 4, 2026, 15:42

ASCO26 Research Flags Elevated Maternal Mortality Risk in Pregnant Women With Myeloproliferative Neoplasms – Hematology Advisor

Hematology Advisor shared a post on LinkedIn:

“New research from ASCO26 shows higher maternal mortality rates for pregnant women diagnosed with myeloproliferative neoplasms MPNs.

The physiological hypercoagulability of pregnancy, compounded by MPN-driven erythrocytosis or thrombocytosis, severely amplifies the risk of life-threatening events across all trimesters and the postpartum window.

Key Areas for Clinical Vigilance:

  • Thrombotic and Vascular Burden: Marked increase in deep vein thrombosis, pulmonary embolism, splanchnic vein thrombosis, and stroke.
  • Obstetric Pathologies: Higher baseline incidence of placental insufficiency, preeclampsia, early miscarriage, and stillbirth.
  • Hemostatic Paradox: Concurrent elevation in bleeding risks, notably postpartum hemorrhage, requiring careful titration of antiplatelet or anticoagulant agents.

Read the article here.”

Hematology Advisor

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anticoagulant agents antiplatelet ASCO26 bleeding risks deep vein thrombosis early miscarriage Fertility Fertility News Hematology Advisor Hemostatic Paradox maternal mortality MPN-driven erythrocytosis notably postpartum hemorrhage Obstetric Pathologies physiological hypercoagulability Placental Insufficiency Preeclampsia pregnancy pregnant women pulmonary embolism reproductive health Reproductive Medicine splanchnic vein thrombosis stillbirth stroke thrombocytosis Thrombotic and Vascular Burden
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