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Somil Singhal: ICSI Procedure Step-by-Step
Photo: DepositPhotos
Sep 9, 2026, 13:26

Somil Singhal: ICSI Procedure Step-by-Step

Somil Singhal, Medical Doctor at AIIMS (All India Institute of Medical Sciences, New Delhi), shared on LinkedIn:

“ICSI Procedure Step by Step

The ICSI procedure usually takes place as part of in vitro fertilization

Here’s how it typically works:

  1. Ovarian Stimulation: The woman undergoes hormonal treatment to stimulate her ovaries to produce multiple eggs.
  2. Egg Retrieval: Once the eggs are mature, retrieves them from the woman’s ovaries using a minor surgical procedure.
  3. Sperm Collection: On the same day as egg retrieval, the man provides a sperm sample. If there are issues with sperm quality or quantity, it is better to obtain a sperm sample through other methods, such as a testicular biopsy.
  4. ICSI: Under a microscope, select a healthy-looking sperm and inject it directly into an egg using a fine needle.
  5. Fertilization: After the sperm injection, it is necessary to monitor the eggs to see if fertilization occurs. If fertilization is successful, then transfer the embryos into the uterus.
  6. Embryo Transfer: A few days after fertilization, transfer one or more embryos into the uterus.

The goal is for the embryos to implant and lead to a successful pregnancy.”

ICSI Success Rates and Risks

ICSI can significantly improve the chances of fertilization, even in cases of severe male infertility. However, like any medical procedure, it’s important to understand both the benefits and risks.

ICSI Success Rates: The success of ICSI varies depending on several factors, including the age of the woman, the quality of the eggs and sperm, and the expertise of the medical team. On average, the success rate of ICSI ranges from 40% to 50% per cycle.

ICSI Risks: While ICSI is generally safe, there are some risks involved. These may include the possibility of genetic abnormalities in offspring, although the risk is very low. Additionally, there’s a small chance of damage to the eggs or embryos during the injection process.

Risks associated with ICSI

  • Excessive response to fertility drugs (ovarian hyperstimulation syndrome)
  • Multiple birth (twins and triplets)
  • Premature labour and low birth weight
  • A small increased risk of birth defects compared with spontaneously conceived babies

What to do with unused embryos

Sometimes people have embryos in storage that they don’t intend to use. Most commonly this is because they have completed their family, but for some people, health reasons prevent them from using their stored embryos. At the end of the storage time limit, which is 5 years, it is necessary to decide what to do with unused embryos.

There are 4 options available:

  1. Apply for an extension of storage time.
  2. Dispose of the embryos.
  3. Let the embryos be used for research.
  4. Donate the embryos to an infertile person or couple.

Couples who have frozen embryos that they are not intending to use often find it difficult to decide what to do with them.”

Proceed to the video attached to the post.

Other articles featuring Somil Singhal on Fertility News.

embryo transfer Embryology Fertility Fertility News ICSI ICSI procedure Intracytoplasmic Sperm Injection IVF OBGYN ovarian stimulation reproductive health Reproductive Medicine Somil Singhal Women’s Health
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