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Ryan Marquardt: Inflammation, Gynecological Disease, and Infertility
Ryan Marquardt/LinkedIn
Nov 14, 2025, 13:48

Ryan Marquardt: Inflammation, Gynecological Disease, and Infertility

Ryan Marquardt, Postdoctoral Fellow at the National Institutes of Health, shared a post on LinkedIn:

“NEW PAPER ALERT

Have you ever been curious about the connections between uterine inflammation, gynecological disease, and infertility? I’m excited to share our new paper that addresses this topic! In it we describe our findings that a transcription factor called serum response factor (SRF) is dysregulated in some women with endometriosis and that, in mice, disrupting its activity leads to severe uterine inflammation, fibrosis, and infertility. I’m incredibly thankful to everyone who contributed to this project and am hopeful that it helps push forward the ongoing research in the field!

Read it for free here.”

Title: Serum response factor is essential for endometrial function and prevention of inflammatory fibrosis

Authors: Ryan M. Marquardt, Sara A. Grimm, San-Pin Wu, Peter F. Lais, Shu-Yun Li, Xin Xu, Erin Smithberger, David Cunefare, Charan Ganta, David Olson, Eunhee M. Jeong, Jae-Wook Jeong, Bruce A. Lessey, John P. Lydon, Francesco J. DeMayo

Ryan Marquardt: Inflammation, Gynecological Disease, and Infertility

Stay updated on all scientific advances in the field of fertility with Fertility News.

Bruce A. Lessey Charan Ganta David Cunefare David Olson Erin Smithberger Eunhee M. Jeong Fertility Fertility News Francesco J. DeMayo Gynecological Disease infertility inflammation Jae-Wook Jeong John P. Lydon OBGYN Peter F. Lais Ryan M. Marquardt Ryan Marquardt San-Pin Wu Sara A. Grimm Shu-Yun Li Xin Xu
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