Exploring Future Strategies for Embryo Selection in IVF – Reproductive BioMedicine Online
Reproductive BioMedicine Online shared a post on LinkedIn about a paper by Santiago Munne et al. published in RBMO:
“In this extensive Review article, Santiago Munne, Jose A. Horcajadas Almansa, Michelle Louise Seth-Smith, Michelle Perugini, and Darren Griffin evaluate the efficacy of three promising alternative technologies for assessment of ploidy status in IVF embryos (PGT-A):
AI powered algorithmic selection software – can classify the chance of an embryo implanting with an average of 0.7 AUC (area under the curve), at up to 10 times the speed of manual scoring however it is still inferior to invasive PGT-A.
Non-invasive methods using cell-free DNA – are described as having improved significantly in recent years and with sequencing costs falling have the potential to reach 100% concordance with PGT-A.
Metabolomics – remains the least applied technique, but shows the potential to identify euploid embryos that metabolically are incapable of implanting, with minimal IVF protocol change.
The authors say that future non-invasive treatment regimes for embryo selection may involve a combination of two, or even all three, of these approaches.
Read the full Review for free from issue 51.5 now.”
Title: Non-invasive selection for euploid embryos: prospects and pitfalls of the three most promising approaches
Authors: Santiago Munne, Jose A. Horcajadas Almansa, Michelle Louise Seth-Smith, Michelle Perugini, Darren Griffin
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Aug 9, 2026, 15:00Kiani Davis: Providing Information Isn’t Necessarily the Same As Providing Education
-
Aug 9, 2026, 13:525 Evidence-Based Reasons Not to “Just Keep Trying” – Fertility Plus
-
Aug 9, 2026, 13:34The Future of Embryology Depends on How We Train the Next Generation – ASRM
-
Aug 9, 2026, 13:22Ritik Shukla: Menopause Is Not the End of Vitality – It’s the Beginning of a New Chapter
-
Aug 9, 2026, 12:57Szabó Gábor: 2 Imaging Modalities for Detecting Endometriosis
-
Aug 9, 2026, 12:36Shehab Gamal: Your Fertility Might Be Sitting in Your Fridge
-
Aug 9, 2026, 12:14Why Language Shapes PMOS Care – PCOS Awareness Association
-
Aug 9, 2026, 11:46Veekesh Roy: A Simple Overview of the Science Behind IVF and Modern Reproductive Medicine
-
Aug 9, 2026, 11:38Diet and Fertility in Women: Expert Insights with Bunafsha Subhani – Valley Fertility Centre