Mohammad Haddadi: New Insights on Chronic Histiocytic Intervillositis Outcomes
Mohammad Haddadi, Medical Doctor at Aflatoon Clinic, shared a post on LinkedIn about a paper published in International Journal of Gynecological Pathology:
“Proud to share our latest publication in the International Journal of Gynecological Pathology, ‘Placental Chronic Histiocytic Intervillositis: Pregnancy Outcomes and Complications – A Systematic Review and Meta-Analysis’.
Chronic histiocytic intervillositis (CHI) is a rare but serious placental inflammatory condition with profound implications for pregnancy outcomes. In this systematic review and meta-analysis, we synthesized evidence from 12 studies encompassing 568 pregnancies to better quantify maternal and neonatal risks associated with idiopathic CHI.
Key findings:
- 40% pooled frequency of intrauterine growth restriction (IUGR)
- 55% live birth rate
- 20% intrauterine fetal death (IUFD)
- Findings remained consistent in sensitivity analyses restricted to low-risk studies
Our results highlight the substantial burden of adverse outcomes associated with CHI and reinforce the need for early recognition, standardized diagnostic criteria, and targeted management strategies in affected pregnancies.
Grateful to work with an excellent team of collaborators. Looking forward to seeing how these findings contribute to improved placental pathology awareness and maternal–fetal care.
Link.”
Title: Placental Chronic Histiocytic Intervillositis: Pregnancy Outcomes and Complications, a Systematic Review and Meta-Analysis
Authors: Elena Ghotbi, Zeinab Mansouri, Alireza Azarboo, Nasim Eshraghi, Marjan Ghaemi, Mohammad Haddadi, Zahra Panahi, Sedigheh Hantoushzade
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Sep 15, 2026, 18:18A PCOS Diagnosis Can Stay in the Background of Every Fertility Conversation – Banker IVF and Women’s Hospital
-
Sep 15, 2026, 18:15The Difference Between Ovulation Induction and Ovarian Stimulation – Fertility Plus
-
Sep 15, 2026, 18:13Ritu Anand: What Would I Tell an IVF Couple in the 1980s?
-
Sep 15, 2026, 18:11STP Curriculum Feedback Survey – The Association of Reproductive and Clinical Scientists
-
Sep 15, 2026, 18:09Khushi Mishra: ICSI – Where Precision Meets the Possibility of Life
-
Sep 15, 2026, 18:06Khalil Faaed: The Future of niPGT-A Is Not Just Non-Invasive…
-
Sep 15, 2026, 18:04Anuradha Housnur: ICSI Is Not About Injecting the Sperm…
-
Sep 15, 2026, 18:02Snehal Kaware: Can an Oocyte With a Vacuole Still Fertilize?
-
Sep 15, 2026, 17:59Kanishka Gaur: Amenorrhea Is a Symptom, Not a Diagnosis