Asma Khalil: A Step-by-Step Guide to Performing Ophthalmic Artery Doppler for Pre-Eclampsia Screening
Asma Khalil, Professor of Maternal Fetal Medicine at St. George’s Hospital, shared on LinkedIn about a recent paper she co-authored with Thomas Hanton, published in Best Practice and Research Clinical Obstetrics and Gynaecology:
“New publication: How to measure ophthalmic artery Doppler for pre-eclampsia screening.
I’m delighted to share our latest article, co-authored with Dr. Thomas Hanton, now published in Best Practice and Research Clinical Obstetrics and Gynaecology.
The article provides a practical, step-by-step guide to performing ophthalmic artery Doppler, with a focus on achieving consistent, reproducible measurements for clinical practice and research.
Key takeaways include:
- Why the PSV2/PSV1 ratio is a powerful, non-invasive marker relevant to pre-eclampsia.
- Evidence showing improved second-trimester screening performance when ophthalmic artery Doppler is incorporated into prediction models.
- A detailed acquisition protocol covering insonation technique, Doppler settings and image optimisation.
- Practical guidance on safety, reproducibility and implementation.
- The potential role of ophthalmic artery Doppler as an accessible screening tool, particularly in low-resource settings.
I hope this practical guide will support clinicians, sonographers and researchers working to improve the early detection of pre-eclampsia.
Many thanks to my co-author, Dr. Thomas Hanton, for this excellent collaboration.”
Thomas Hanton, co-author of the article and Clinical Fellow at Royal College of Obstetricians and Gynaecologists (RCOG), shared this post, adding:
“We have recently published a guide on measuring ophthalmic artery Doppler for pre-eclampsia screening. Thank you, Prof Asma Khalil, for the opportunity and mentorship.”

Title: How to measure ophthalmic artery Doppler for pre-eclampsia screening
Authors: Thomas Hanton and Asma Khalil
You can read the Full Article in Best Practice and Research Clinical Obstetrics and Gynaecology.

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