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PGT-A Integration Into PGT-M Protocols in Young ART-Naïve Patients – RBMO
RBMO/LinkedIn
Jul 19, 2026, 05:45

PGT-A Integration Into PGT-M Protocols in Young ART-Naïve Patients – RBMO

Reproductive BioMedicine Online (RBMO) shared a post on LinkedIn:

“This retrospective cohort study explored the clinical value of integrating genome-wide aneuploidy screening into protocols for preimplantation genetic testing for monogenic disorders (PGT-M), forming what we refer to as coPGT-M.

The study by Frauke Vanden Meerschaut and team at Ghent University Hospital focused on a cohort of young ART-naïve patients, for whom the natural prevalence of euploid embryos is relatively high, and aims to determine whether this combined genetic approach could enhance clinical outcomes in a meaningful way.

The findings suggest that integrating PGT-A into PGT-M protocols in this population may be associated with lower early pregnancy loss rates and higher live birth rates per transfer, without compromising cumulative outcomes. These results indicate that coPGT-M could represent a promising approach within selected PGT-M contexts.

RBMO subscribers can read the full paper ahead of press from issue 53.3, now.”

Title: Integrating PGT-A into PGT-M protocols in young ART-naïve patients undergoing single embryo transfer

Authors: Frauke Vanden Meerschaut, Emma Deweirdt, Margot Kint, Machteld Baetens, Sofie Symoens, Kelly Tilleman, Björn Menten, Ilse De Croo, Lien Dhaenens, Sandra Janssens, Dominic Stoop

PGT-A Integration Into PGT-M Protocols in Young ART-Naïve Patients – RBMO

Stay updated on all scientific advances in the field of fertility with Fertility News.

Björn Menten Clinical Outcomes coPGT-M cumulative outcomes Dominic Stoop early pregnancy loss rates Emma Deweirdt Fertility Fertility News Frauke Vanden Meerschaut genome-wide aneuploidy Ilse De Croo Kelly Tilleman Lien Dhaenens Machteld Baetens Margot Kint monogenic disorders (PGT-M) natural prevalence PGT-A PGT-M protocols Preimplantation Genetic Testing Reproductive BioMedicine Online (RBMO) reproductive health Reproductive Medicine retrospective cohort study Sandra Janssens Sofie Symoens
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