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New Research on Oocyte Quality Challenges in DOR – RBMO
RBMO/LinkedIn
Feb 22, 2026, 17:50

New Research on Oocyte Quality Challenges in DOR – RBMO

Reproductive BioMedicine Online shared a post on LinkedIn about a paper by En-Qi Yan et al. published in RBMO:

“How does diminished ovarian reserve (DOR) affect euploid blastocyst rates, and how many embryos need to be biopsied for women with DOR and those without DOR to achieve one euploid embryo?

The findings of this new study show that DOR patients have fewer euploid embryos but similar euploidy rates and pregnancy outcomes compared to non-DOR patients within the same age group. Furthermore, this research found that for women >39 years, repeated oocyte aspirations offer minimal benefit in increasing the acquisition of euploid embryos.

The limited embryo quantity remains the predominant challenge for DOR patients, rather than inferior oocyte quality.

RBMO subscribers can read the full paper from our February issue, now.”

Title: Oocyte quality in women with diminished ovarian reserve: not as poor as assumed

Authors: En-Qi Yan, Hong-Xia Chen, Yuan-Li Li, Lei Jin, Bing-Xin Ma

RBMO

Stay updated on all scientific advances in the field of fertility with Fertility News.

Age-Related Fertility Assisted Reproductive Technology Bing-Xin Ma diminished ovarian reserve DOR Embryo Biopsy embryo development Embryo Quality En-Qi Yan Euploid Blastocysts Fertility Fertility News fertility outcomes fertility research Genetic Testing Hong-Xia Chen IVF Success Rates Lei Jin Oocyte Aspiration Pregnancy Outcomes RBMO Reproductive BioMedicine Online reproductive health Reproductive Medicine Yuan-Li Li
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