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Sandro Graca: Understanding the PCOS-Obesity Link
Sandro Graca/LinkedIn
Jan 6, 2026, 13:44

Sandro Graca: Understanding the PCOS-Obesity Link

Sandro Graca, Visiting Lecturer at University of Wolverhampton, shared a post on LinkedIn about a paper by Helena Teede et al. published in Global Reproductive Health:

“‘PCOS demonstrates bidirectional relationships with obesity: elevated BMI increases PCOS risk while PCOS predisposes to weight gain, with Mendelian randomization confirming causal relationships. Higher BMI exacerbates PCOS severity through enhanced hyperandrogenism and insulin resistance, driving ovulatory dysfunction, infertility, pregnancy complications, and elevated long-term risks, including diabetes and cardiovascular disease.’

Read the full article.

Authors: Prof Helena Teede and Dr Chau Thien Tay

Global Reproductive Health 10(4):e0122, Winter 2025.”

Sandro Graca

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body mass index cardiovascular disease Chau Thien Tay Diabetes Risk Fertility Fertility News Health Risks Helena Teede Hormonal Imbalances Hyperandrogenism Insulin Resistance Ovulatory Dysfunction Polycystic Ovary Syndrome Pregnancy Complications reproductive health Sandro Graca
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