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Sonal Pendharkar Kulkarni: When the Vaginal Microbiome Is Off, Everything Is Affected!
Dec 14, 2025, 08:29

Sonal Pendharkar Kulkarni: When the Vaginal Microbiome Is Off, Everything Is Affected!

Sonal Pendharkar Kulkarni, CSO and Co-founder of Uvisa Health, shared a post on LinkedIn about a paper by Axel Skafte-Holm et al. published in The Lacnet:

“The science is ctching up to what many women already feel: When the vaginal microbiome is off, everything is affected!

A fascinating new Danish collaborative research by Axel Skafte-Holm and Jørgen Skov Jensen at Statens Serum Institut tracked nearly 2,000 pregnant women and the findings really resonated with my initial understanding of the vaginal microbiome and it’s far-reaching impact on women’s health, including pregnancy:

Lactobacillus crispatus rich vaginal microbiome was more associated with healthy pregnancies
Ureaplasma spp and Mycoplasma hominis were not associated with loss, an important nuance!
Vaginal dysbiosis, i.e. a mixed and diverse vaginal microbiome was significantly associated with pregnancy loss

What stood out most?

  • It’s the overall stability and balance of the microbiome that matters the most.
  • A stable microbiome sets the trajectory for what happens next.

This is exactly why at UVISA Health , we’re focused on creating solutions that support women’s natural microbial balance and not disrupt it.

Congratulation to all the authors…great work.”

Title: The role of the vaginal microbiota, sexually transmitted infections, ureaplasmas, and Mycoplasma hominis in pregnancy loss: a prospective study in pregnant women in Denmark

Authors: Axel Skafte-Holm, Thomas Roland Pedersen, Anna Sandager, Rikke Damkjær Maimburg, Camilla Lindahl, Anja Vad Søndergaard, Kirsten Salado-Rasmussen, Anna Cäcilia Ingham, Niels Uldbjerg, Jørgen Skov Jensen

Read the full article.

Sonal Pendharkar Kulkarni: When the Vaginal Microbiome Is Off, Everything Is Affected!

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