Malika Mirwani: Sperm DNA Fragmentation and What It Means for Male Fertility
Malika Mirwani, Corporate Business Development Manager at Pusat Fertilitas Bocah Indonesia, shared a post on LinkedIn:
“Sperm DNA Fragmentation (SDF): What It Means for Male Fertility
While most fertility checks focus on sperm count, motility, and morphology – there’s another important factor that often goes unseen: DNA quality.
Sperm DNA Fragmentation (SDF) measures the integrity of the sperm’s genetic material. High SDF levels can reduce fertilization, embryo development, and pregnancy success – even when standard semen results look normal.
A 2025 review of 174 studies by Joaquín Llácer et al. found that:
- High SDF is associated with lower chances of natural conception and IUI success.
- It’s linked to poorer fertilization and embryo quality, and higher miscarriage risk.
- It can often be improved through lifestyle changes, antioxidants, or varicocele repair.
However, results vary – there’s still no universal cutoff or standardized test, and findings can depend on egg quality and female age.
That’s why experts recommend SDF testing as a second-line tool: valuable for couples with unexplained infertility, recurrent miscarriage, or repeated IVF failure.
At Pusat Fertilitas Bocah Indonesia, SDF testing is now available as part of our comprehensive male fertility evaluation – helping couples identify underlying factors and personalize treatment plans more effectively.
Because fertility care isn’t just about numbers – it’s about understanding the full story behind them.”
-
Oct 11, 2025, 06:44The Global IVF Market Is Set to Reach $65B by 2032 – Meddilink
-
Feb 4, 2026, 00:43Join the 2026 Rising Stars Webinar On February 11 – SSR
-
Feb 4, 2026, 00:18Dalia Alqarni: Urinary Incontinence’s Impact on Women’s Health
-
Feb 4, 2026, 00:16New Study Reveals IVF Success for Women With Endometriosis – Fertility Plus
-
Feb 4, 2026, 00:13Tamuka Chekero: Exploring Relational Autonomy in Infertility Across Cultures
-
Feb 2, 2026, 13:04Optimal GnRH Agonist Dosage for Oocyte Maturation – Fertility and Sterility
-
Feb 2, 2026, 12:39Family Planning Challenges for Women with Lupus – The Lupus Foundation of Australasia
-
Feb 2, 2026, 12:17Anis Feki: Innovative Strategies for Bowel Endometriosis Management
-
Feb 2, 2026, 12:10Revolutionizing Testicular Cell Cultivation with 3D Bioprinting – School of Infection, Inflammation and Immunology, University of Birmingham
-
Feb 2, 2026, 12:07Cesar Diaz Garcia: Age and Its Impact on Male Fertility