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Leah Flatman: Patterns of Use and Discontinuation for TNF Inhibitors in Pregnant Women
Nov 9, 2025, 06:49

Leah Flatman: Patterns of Use and Discontinuation for TNF Inhibitors in Pregnant Women

Leah Flatman, Postdoctoral Fellow at Centre de recherche Azrieli du CHU Sainte-Justine, shared a post by The Journal of Rheumatology on LinkedIn:

“I am very grateful to The Journal of Rheumatology for publishing our recent study on TNF inhibitor use during pregnancy: Patterns of Use and Discontinuation for Tumor Necrosis Factor Inhibitors in Pregnant Women: Insights From a Real-World Sample.

I am also grateful to Laura Andreoli, Mette Julsgaard, and Karen Schreiber for their thoughtful commentary. Together, our articles highlight a key reality in pregnancy research: it has taken over a decade for TNF inhibitors to be used confidently in pregnancy, underscoring the need to generate safety data earlier in drug development.

We fully agree that better-informed decisions start with stronger evidence early on. Integrating pregnancy data into clinical development could make a real difference for women with chronic diseases who are planning a family.

It’s encouraging to see regulatory frameworks evolving, and collaborations between researchers, clinicians, and regulators will be essential to ensuring safe and effective treatments for mothers and babie.”

Quoting The Journal of Rheumatology’s post:

“Research Article

Patterns of Use and Discontinuation for Tumor Necrosis Factor Inhibitors in Pregnant Women: Insights From a Real-World Sample.”

Title: Patterns of Use and Discontinuation for Tumor Necrosis Factor Inhibitors in Pregnant Women: Insights From a Real-World Sample

Authors: Leah K. Flatman, Sasha Bernatsky, Anick Bérard, Évelyne Vinet

Leah Flatman: Patterns of Use and Discontinuation for TNF Inhibitors in Pregnant Women

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