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Roberto Costillas Perez: The Endometrial Microbiome Is a Key Factor for Uterine Receptivity
Roberto Costillas Perez/LinkedIn
Dec 14, 2025, 10:29

Roberto Costillas Perez: The Endometrial Microbiome Is a Key Factor for Uterine Receptivity

Roberto Costillas Perez, Founder and CEO at Fertypharm, shared a post on LinkedIn:

“The endometrial microbiome is a key factor for reproductive health and uterine receptivity.

A balanced microbiome, dominated by Lactobacillus improves embryo implantation and reproductive success.
In contrast, microbial dysbiosis is associated with implantation failure and complications such as endometritis.

  • Studies show that patients with a healthy endometrial microbiome are up to 30% more likely to have a successful pregnancy after assisted reproduction.
  • In addition, the microbiome influences the immune response and gene expression of the endometrium, modulating an optimal environment for implantation.

This opens up new therapeutic opportunities to treat infertility.

The endometrial microbiome is a key factor for reproductive health and uterine receptivity.

A balanced microbiome, dominated by Lactobacillus, enhances embryo implantation and reproductive success.
In contrast, microbial dysbiosis is linked to implantation failure and complications like endometritis.

  • Studies show patients with a healthy endometrial microbiome have up to a 30% higher chance of successful pregnancy after assisted reproduction.
  • The microbiome influences immune responses and endometrial gene expression, creating an optimal environment for implantation.

This opens new therapeutic opportunities to treat infertility.”

Title: Endometrial Microbiome and Reproductive Receptivity: Diverse Perspectives

Authors: Galina Stoyancheva, Nikolina Mihaylova, Maria Gerginova, Ekaterina Krumova

Read the full article.

Roberto Costillas Perez: The Endometrial Microbiome Is a Key Factor for Uterine Receptivity

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