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Catalina Cristina Nazare: Overcoming Total Globozoospermia 
Nov 3, 2026, 17:08

Catalina Cristina Nazare: Overcoming Total Globozoospermia 

Catalina Cristina Nazare, Former Embryologist at Gynera Clinic, shared on LinkedIn:

”Overcoming Total Globozoospermia

In cases of total globozoospermia, achieving a blastocyst can seem like an insurmountable challenge. The complete absence of an acrosome in these round-headed sperms means they lack the enzymatic capacity for fertilization.

I am incredibly proud to share a recent case that demonstrates the intersection of advanced clinical science and unwavering patient hope.

The Case Journey:

  • 15 Oocytes collected.
  • 12 Mature Oocytes identified.
    Total fertilization failure was a high risk due to the Globozoospermia. I applied artificial oocyte activation (AOA).
  • 4 Oocytes Fertilized.
    From these four, a miracle occurred.

I am thrilled to present two beautiful blastocysts, now cryopreserved.

Takeaway: Total globozoospermia is a complex and severe form of male infertility, but with specialized techniques it is no longer an absolute barrier.

Congratulations to the courageous couple for emotional victory.”

Catalina Cristina Nazare: Overcoming Total Globozoospermia 

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