Christopher Robinson: Hilary O.D. Critchley, a Physician-Scientist Who Transformed the Understanding of Menstruation!
Christopher Robinson, Associate Professor Maternal Fetal Medicine at University of South Carolina, shared a post on LinkedIn:
“AJOG Giants in Obstetrics and Gynecology: Hilary O.D. Critchley: a physician-scientist who transformed the understanding of menstruation – The mechanisms whereby progesterone withdrawal leads to menstruation – Progesterone withdrawal activates many pathways. Prominent among these are those releasing vasoactive agents. Chemotactic agents, which synergize with vasoactive agents, are also expressed. There is no doubt that MMPs, which degrade the interstitial matrix of the endometrium, play a major role in the menstruation process, but their origin is uncertain. MMPs can be released from both resident endometrium stromal cells and invading leukocytes.”
Title: Giants in Obstetrics and Gynecology: Hilary O.D. Critchley: a physician-scientist who transformed the understanding of menstruation
Authors: Roberto Romero
Read the full article.
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