The European Fertility Society/LinkedIn
Dec 17, 2025, 15:11
When Immunity Blocks Fertility – EFS
The European Fertility Society (EFS) shared a post on LinkedIn:
“When the Immune System Disrupts Fertility
Not all fertility challenges are hormonal or anatomical. Increasing evidence shows that the immune system can determine whether an embryo implants, a pregnancy continues, and how the placenta develops.
Who is most at risk?
- Patients with unexplained RIF – often showing elevated NK cell activity or a Th1-skewed immune profile.
- Women with autoimmune diseases – from SLE to APS, where autoantibodies may damage placental tissues and drive pregnancy loss.
- Those with endometriosis, microbiome imbalance, or PCOS – conditions marked by chronic inflammation.
- Individuals over 35, with obesity, GDM, or a history of pre-eclampsia – where immunosenescence and metabolic inflammation disrupt maternal–foetal tolerance.
- Read the full professional article by Julie Morgan, published via the European Fertility Society.
This article highlights just how crucial immune balance is in reproductive medicine and why understanding immunological vulnerabilities can transform treatment outcomes.
Dive deeper into our Education Section for expert articles, webinars, and clinical insights on fertility care.”
Stay updated on all scientific advances in the field of fertility with Fertility News.
Advanced Maternal Age
autoantibodies
Autoimmune Diseases
Chronic Inflammation
EFS
Elevated NK Cells
embryo implantation
Endometriosis Research
Fertility
Fertility News
immune system
Julie Morgan
Microbiome Imbalance
Obesity Impact
placental development
Polycystic Ovary Syndrome
pregnancy loss
Recurrent Implantation Failure
Reproductive Immunology
Th1 Immune Profile
The European Fertility Society
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