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5 Evidence-Based Reasons Not to “Just Keep Trying” – Fertility Plus

Fertility Plus/LinkedIn

Aug 9, 2026, 13:52

5 Evidence-Based Reasons Not to “Just Keep Trying” – Fertility Plus

Fertility Plus shared on LinkedIn:

“5 Evidence-Based Reasons Not to ‘Just Keep Trying’

For women over 35, the timing of decisions around fertility is crucial. Here’s a ranked countdown of five compelling reasons to act sooner:

5. 97% of natural conceptions occur within 24 months. Waiting into a third year adds a negligible 1.7%.

4. Every six months of waiting in unexplained subfertility lowers next-year success rates significantly (27% – 20% – 15% – 13%).

3. After two years of trying, monthly conception odds can dwindle to just 1–5%.

2. Fecundability declines by 40–60% between ages 37 and 45, with a steep drop starting before age 40.

1. For long-standing unexplained infertility, IVF offers about a 38% chance of clinical pregnancy versus just 13% from continued waiting.

The takeaway? For women aged 35+, timing is the treatment decision that matters most.

Gnoth et al., Human Reproduction 2003. Declining next-year chances with continued waiting (27-13%): van Eekelen et al., Human Reproduction 2017. Monthly fecundity 1–5% in established subfertility: Evers JLH, The Lancet 2002. Age-related fecundability decline (40–60%): ACOG/ASRM Committee Opinion No. 589, 2014.”

5 Evidence-Based Reasons Not to “Just Keep Trying” – Fertility Plus