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Subtle Chromosome Swaps Don’t Stand in the Way of IVF – Fertility Plus
Nov 13, 2025, 18:01

Subtle Chromosome Swaps Don’t Stand in the Way of IVF – Fertility Plus

Fertility Plus shared a post on LinkedIn:

“What if your chromosomes carried a tiny swap no one could see?

Subtle translocations – minute rearrangements of genetic material  once raised real concern in IVF. Could they lower embryo quality? Reduce pregnancy chances? Cause miscarriages?

A new study by Yun Wang et al. (2024) brings clarity – and calm. Analysing embryos through PGT-SR, researchers found no difference in euploid blastocyst rates. What are the outcomes of pregnancy, miscarriage, and live births? All comparable to non-carriers.

In short: these tiny rearrangements don’t impact embryo health when modern genetic testing is used. Science once feared what precision genetics now reassures!

For patients, it’s powerful news – subtle translocations are not a barrier to success. For clinicians, it reaffirms the strength of PGT-SR as a stabilising force in reproductive genetics.”

Fertility Plus

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