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New Guidelines on Frozen Embryo Transfer Released – RBMO
Reproductive BioMedicine Online/rbmojournal.com
Dec 21, 2025, 06:53

New Guidelines on Frozen Embryo Transfer Released – RBMO

Reproductive BioMedicine Online (RBMO) shared a post on LinkedIn:

“We are pleased to publish a new official Guideline from the Canadian Fertility and Andrology Society.

Authored by Julio Saumet, Elias M. Dahdouh, Camille Sylvestre, Heather Shapiro, Jason Min, Jeff Roberts, Kimberly Liu, Maria Velez, Neal Mahutte, Sony Sierra, and William Buckett, the guideline  provides evidence-based recommendations drawn exclusively from recent randomized control trials, for the clinical management of frozen embryo transfer (FET).

In Canada, the incidence of freeze all cycles has increased from 24% to 78% over the last decade. While a freeze-all strategy can be a pivotal tool for the prevention of ovarian hyper stimulation syndrome (OHSS), the available data do not support its routine use for improving live birth rates (LBR), reducing pregnancy loss (PL), or enhancing obstetric outcomes in the general IVF population. Similarly, ovulatory FET cycles do not offer advantages over artificial FET cycles for live birth or pregnancy loss, and current evidence remains conflicting for obstetric and perinatal outcomes. The route of progesterone administration in artificial FET cycles does not significantly affect live birth or pregnancy loss rates.

Ultimately, the Guideline states that FET approaches should be individualized based on patient characteristics and clinical context, with ongoing research required to optimize outcomes and inform best practices.

Published open access, the Guideline can be read in full for free from our in-press articles section now.”

Title: Approaches to frozen embryo transfer: a Canadian Fertility and Andrology Society (CFAS) guideline

New Guidelines on Frozen Embryo Transfer Released – RBMO

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Camille Sylvestre Elias M. Dahdouh Fertility Fertility News Heather Shapiro IVF Jason Min Jeff Roberts Julio Saumet Kimberly Liu Live Birth Rates Maria Velez Neal Mahutte OHSS ovarian hyper stimulation syndrome reproductive health Reproductive Medicine Sony Sierra William Buckett
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