Reem Prince: Fetal Anomaly Case on Semilobar Holoprosencephaly
Reem Prince, Radiology consultant at TechnoScan, shared a post on LinkedIn:
“Fetal Anomaly Case | Semilobar Holoprosencephaly
A prenatal ultrasound case demonstrating features of semilobar holoprosencephaly.
Key neurosonographic findings:
- Single midline ventricular cavity
- Fused thalami
- Partial absence of interhemispheric fissure
- Absent cavum septum pellucidum
3D imaging revealed associated midline facial abnormalities.
An associated ventricular septal defect (VSD) was also identified.
Holoprosencephaly represents a spectrum of forebrain malformations with strong association to chromosomal abnormalities, particularly trisomy 13.
Genetic counseling and further evaluation are essential in such cases.
This case highlights the importance of systematic fetal neurosonography and correlation with extracranial anomalies.”

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