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Wajeeha Shahid: Unraveling Genetic Factors in Male Infertility
Dec 17, 2025, 17:09

Wajeeha Shahid: Unraveling Genetic Factors in Male Infertility

Wajeeha Shahid, Molecular Technologist at The Aga Khan University Hospital, shared a post on LinkedIn:

“Case Report
Clinical History

The patient is a 33-year-old male presenting for an infertility workup. The couple reports an inability to conceive naturally for more than one year. Initial clinical findings (e.g., semen analysis results, physical examination findings) should be documented. There is no reported family history of recurrent miscarriages or known genetic conditions.

Laboratory Methods

Cytogenetic analysis was conducted on cultured peripheral blood lymphocytes using standard G-banding techniques.

Results

Karyotype: 45,XY,dic(13;18)(p11.2;q23)[20]

Description:

Analysis of all 20 metaphases revealed an abnormal male chromosome complement characterized by 45 chromosomes. The finding is a dicentric translocation involving chromosomes 13 and 18, with breakpoints at 13p11.2 and 18q23.”

Wajeeha Shahid

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Abnormal Karyotype Chromosomal abnormalities Cytogenetic Analysis Fertility Fertility Assessment Fertility News G-Banding Techniques Genetic Conditions Genetic Testing Infertility Diagnosis Infertility Workup Karyotype Analysis male infertility Male Reproductive Health Peripheral Blood Lymphocytes reproductive health semen analysis Wajeeha Shahid
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