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Carl Petrus Linge: Study Identifies New Antibody Linked to Thrombosis Risk in SLE
Carl Petrus Linge/LinkedIn
Mar 7, 2026, 03:41

Carl Petrus Linge: Study Identifies New Antibody Linked to Thrombosis Risk in SLE

Carl Petrus Linge, Specialist in Rheumatology at Region Skåne, shared a post on LinkedIn:

“Thrombosis is a major clinical problem in SLE, not fully explained by antiphospholipid antibodies.

In our study, now published in Haematologica, we report:

  • Anti-glycoprotein V (GPV) antibodies independently associated with thrombotic events in SLE
  • C3 independently associated with thrombosis in multivariable Cox regression analyses

These findings support previously unrecognized platelet-complement and platelet-directed antibody mechanisms contributing to thrombotic risk beyond APS pathways.

Grateful to all collaborators involved in this work, including Rick Kapur, Anders Bengtsson and John Semple!”

Title: Platelet glycoprotein V autoantibodies and complement C3 are associated with thrombosis in systemic lupus erythematosus

Authors: Anders A. Bengtsson, Elsa Grenmyr, Andreas Jönsen, Robin Kahn, John W. Semple, Leendert Porcelijn, Rick Kapur, Carl Petrus Linge

Carl Petrus Linge: Study Identifies New Antibody Linked to Thrombosis Risk in SLE

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Anders A. Bengtsson Anders Bengtsson Andreas Jönsen Anti-glycoprotein V Antiphospholipid Antibodies Carl Petrus Linge Elsa Grenmyr Fertility Fertility News John Semple John W. Semple Leendert Porcelijn reproductive health Reproductive Medicine Rick Kapur Robin Kahn SLE Thrombosis Thrombosis Risk
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