Stopping GLP-1 Drugs Before Pregnancy May Impact Maternal Health – Fertility Plus
Fertility Plus shared a post on LinkedIn:
“The Hidden Rebound: The Impact of Stopping Weight-Loss Injections Before Pregnancy
Did you know that stopping weight-loss injections like GLP-1 drugs before pregnancy can lead to unexpected challenges? A major new study reveals that women who discontinued these medications gained over 3 kg more during pregnancy compared to those who never used them.
Key Findings:
- Increased risk of going over recommended weight gain limits
- Higher chances of preterm birth (from 13% to 17%)
- Rising cases of gestational diabetes (15% to 20%)
- Nearly half faced high blood pressure issues
While baby sizes and C-section rates remained similar, the impact on maternal health is significant. Experts suggest a quick ‘rebound’ effect in appetite and metabolism after stopping the drug, compounded by the stress of pregnancy.
If you’re considering pregnancy after using these medications, extra monitoring and support could make all the difference!
Scientific Reference:
Maya J et al. Gestational Weight Gain and Pregnancy Outcomes After GLP-1 Receptor Agonist Discontinuation. JAMA. 2025;334(24)
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