HCG and GnRH Analogue Trigger Failure – Fertility Plus
Fertility Plus shared a post on LinkedIn:
“HCG and GnRH analogue trigger failure
A recent large retrospective analysis has shed light on the effectiveness of different trigger types in IVF cycles. Comparing 2,034 donor GnRHa-trigger cycles with 1,433 hCG-trigger cycles, the study found EFS incidences of 3.5% for GnRHa and 3.1% for hCG, indicating no significant difference between the two methods when executed properly. This aligns with earlier literature citing a 2–7% EFS incidence for hCG triggers, reinforcing that trigger type alone does not appear to increase EFS risk.
J Assist Reprod Genet (2012) 29:249–253
DOI 10.1007/s10815-011-9704-8
Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS Juan C. Castillo and Juan Garcia-Velasco and Peter Humaidan IVF.”
Title: Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS
Author: Juan C Castillo, Juan Garcia-Velasco, Peter Humaidan
Read the full article.

-
Mar 21, 2026, 15:00Samantha Butts Shares Personal and Professional Insights in ASRM Close Up
-
Mar 21, 2026, 14:47Scammers Are Targeting ESHRE2026 Attendees – ESHRE
-
Mar 21, 2026, 14:26No Obvious Harm From Prolonged Oocyte Cryostorage – RBMO
-
Mar 21, 2026, 14:13Empowering Change: Health Systems at the Forefront of Ending FGM/C! – FIGO
-
Mar 21, 2026, 09:56Expanded Carrier Screening: Clinical, Ethical, and Psychosocial Perspectives from Ghent – ESHRE
-
Mar 21, 2026, 09:53Impact of Male Obesity on Embryo Development and Miscarriage Risk – Fertility and Sterility
-
Mar 20, 2026, 17:06Christopher Robinson: AJOG Expert Review on Placenta Accreta After Cesarean
-
Mar 20, 2026, 16:53HCG Failure and Trigger Strategies in IVF – Fertility Plus
-
Mar 20, 2026, 16:38Secure Your Early Bird Ticket for RCOG Annual Professional Development Conference – RCOG
