Malika Mirwani: Sperm DNA Fragmentation and What It Means for Male Fertility
Malika Mirwani, Corporate Business Development Manager at Pusat Fertilitas Bocah Indonesia, shared a post on LinkedIn:
“Sperm DNA Fragmentation (SDF): What It Means for Male Fertility
While most fertility checks focus on sperm count, motility, and morphology – there’s another important factor that often goes unseen: DNA quality.
Sperm DNA Fragmentation (SDF) measures the integrity of the sperm’s genetic material. High SDF levels can reduce fertilization, embryo development, and pregnancy success – even when standard semen results look normal.
A 2025 review of 174 studies by Joaquín Llácer et al. found that:
- High SDF is associated with lower chances of natural conception and IUI success.
- It’s linked to poorer fertilization and embryo quality, and higher miscarriage risk.
- It can often be improved through lifestyle changes, antioxidants, or varicocele repair.
However, results vary – there’s still no universal cutoff or standardized test, and findings can depend on egg quality and female age.
That’s why experts recommend SDF testing as a second-line tool: valuable for couples with unexplained infertility, recurrent miscarriage, or repeated IVF failure.
At Pusat Fertilitas Bocah Indonesia, SDF testing is now available as part of our comprehensive male fertility evaluation – helping couples identify underlying factors and personalize treatment plans more effectively.
Because fertility care isn’t just about numbers – it’s about understanding the full story behind them.”
-
Oct 11, 2025, 06:44The Global IVF Market Is Set to Reach $65B by 2032 – Meddilink
-
Dec 21, 2025, 01:56New Patient Resource on Thyroid Issues in Pregnancy – RCOG
-
Dec 21, 2025, 01:49CDC Releases 2024 Pregnancy Mortality Data – Preeclampsia Foundation
-
Dec 21, 2025, 01:30Caitlin Wyrwoll: New Insights on Maternal Health and Extreme Heat
-
Dec 20, 2025, 10:57Clare Pin-Chia Huang: New Research Links Maternal Diabetes to Pregnancy Risks
-
Dec 20, 2025, 10:53Evaluating Maternal and Neonatal Health in Rheumatoid Arthritis Pregnancies – Hiroki Ozawa
-
Dec 20, 2025, 10:36Enhancing Care for Women Facing Recurrent Pregnancy Loss – SOGC
-
Dec 20, 2025, 05:00Ilana Ferhadian: Celebrating Book Launch
-
Dec 19, 2025, 16:21Launch of National Fertility Plan Marks Public Health Milestone – Collectif BAMP Association
-
Dec 18, 2025, 13:55Insights from Cendrine Siraudin on Fertility Support – Destination Santé