Malika Mirwani: Sperm DNA Fragmentation and What It Means for Male Fertility
Malika Mirwani, Corporate Business Development Manager at Pusat Fertilitas Bocah Indonesia, shared a post on LinkedIn:
“Sperm DNA Fragmentation (SDF): What It Means for Male Fertility
While most fertility checks focus on sperm count, motility, and morphology – there’s another important factor that often goes unseen: DNA quality.
Sperm DNA Fragmentation (SDF) measures the integrity of the sperm’s genetic material. High SDF levels can reduce fertilization, embryo development, and pregnancy success – even when standard semen results look normal.
A 2025 review of 174 studies by Joaquín Llácer et al. found that:
- High SDF is associated with lower chances of natural conception and IUI success.
- It’s linked to poorer fertilization and embryo quality, and higher miscarriage risk.
- It can often be improved through lifestyle changes, antioxidants, or varicocele repair.
However, results vary – there’s still no universal cutoff or standardized test, and findings can depend on egg quality and female age.
That’s why experts recommend SDF testing as a second-line tool: valuable for couples with unexplained infertility, recurrent miscarriage, or repeated IVF failure.
At Pusat Fertilitas Bocah Indonesia, SDF testing is now available as part of our comprehensive male fertility evaluation – helping couples identify underlying factors and personalize treatment plans more effectively.
Because fertility care isn’t just about numbers – it’s about understanding the full story behind them.”
-
Oct 11, 2025, 06:44The Global IVF Market Is Set to Reach $65B by 2032 – Meddilink
-
Nov 5, 2025, 13:34Nibhash Kumar: When Embryos Stop Growing and the Hidden Reasons Behind Early Developmental Arrest
-
Nov 5, 2025, 13:29Ahsan Saeed: DNA From Three Parents Just Stopped a Life-Threatening Disorder Before Birth!
-
Nov 5, 2025, 13:24New Weighted Classification Criteria Refine Antiphospholipid Syndrome Research – Hæmatologi DK
-
Nov 4, 2025, 15:34Optimal Endometrial Thickness Up to 12 mm Boosts Live Birth Rates in IVF – Fertility Plus
-
Nov 4, 2025, 15:20hCG and GnRH Analogue Trigger Show Similar Outcomes in IVF Cycles – Fertility Plus
-
Nov 4, 2025, 15:08Nyakaishiki Mercy: Pregnant Women Shouldn’t Get Leave From Work
-
Nov 4, 2025, 14:55Fewer Preeclampsia Cases Reported With Closed-Loop Insulin Use in Type 1 Diabetic Pregnancies – Medical Xpress
-
Nov 4, 2025, 14:42Meghna Rao: Exploring the Role of the Gut Microbiome in Women’s Reproductive Health
-
Nov 4, 2025, 14:23Fatemeh Zarimeidani: Advancing Care for PCOS-Related Infertility