Hugo Bottemanne: Emotional and Cognitive Effects of Menopause and Hormone Replacement Therapy
Hugo Bottemanne, Psychiatrist at Bicêtre Hospital – MOOD Center Paris-Saclay, shared a post on LinkedIn:
“Depression in women: are there specificities to perimenopause?
Thank you to Agir pour l’Égalité – Think and Do Tank Marie Claire for this symposium dedicated to women’s health in Ministère du Travail, in the presence of Minister Sabrina Roubache, Muriel Pénicaud, Marlène Schiappa Savignac, and a group of researchers and actors from the business world.
Perimenopause is a period of particular vulnerability on the moodic level, linked to hormonal fluctuations, climacteric symptoms and psychosocial changes. There are also brain changes during this period, partially reversible after the onset of menopause, which can modulate the clinical expression of mood disorders.
Regarding the role of hormone replacement therapy, the team from the Department of Psychiatry at University of Cambridge published a study in 2026 in Psychological Medicine evaluating the evolution of brain morphology and mental health in a cohort of 125,000 women, but these results should be interpreted with caution because we still lack data to evaluate this association
Part of the work carried out by the MOODS (Inserm, Paris-Saclay) team and the Service hospitalo-universitaire de Psychiatrie de Bicêtre, in particular through the creation of the ‘Women’s Mental Health’ team (funded by Agence Régionale de Santé Ile-de-France ), aims to respond to the challenges of psychiatric disorders during this period.”
Title: Emotional and cognitive effects of menopause and hormone replacement therapy
Authors: Katharina Zuhlsdorff, Christelle Langley, Richard Bethlehem, Varun Warrier, Rafael Romero Garcia, Barbara J Sahakian
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Oct 29, 2026, 16:22Aysha O’Connor: One of the Hardest Parts of My Own Fertility Journey Was Loneliness…
-
Oct 29, 2026, 16:15Chaithra S K: Preimplantation Genetic Testing Still Requires an Embryo Biopsy
-
Oct 29, 2026, 16:11Filipina Woman’s Journey of Strength, Hope, and Finding Balance While Living with PCOS – PCOS Millennials
-
Oct 29, 2026, 15:58Eric Lameignere: Can DNA Fragmentation in Cumulus Cells Predict ICSI Outcomes?
-
Oct 29, 2026, 15:50Saadat Hassan: Sperm Function Testing – Can Advanced Diagnostics Guide IVF and ICSI Selection?
-
Oct 29, 2026, 15:34Sara Spiro: Celebrating the Stories Members Have Trusted With at Maven Clinic – Here Is Mine
-
Oct 29, 2026, 15:31Dina Ibrahem: 0 Motility, 1 Critical Decision
-
Oct 29, 2026, 15:28AI and Automation in Fertility and Genomics: Pipeline or Pipe Dream? – ARCS
-
Oct 29, 2026, 15:26Michael Schindler: Large Networks or Small Centers – Who Delivers Better Care?