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ASCO26 Research Flags Elevated Maternal Mortality Risk in Pregnant Women With Myeloproliferative Neoplasms – Hematology Advisor
Jun 4, 2026, 15:42

ASCO26 Research Flags Elevated Maternal Mortality Risk in Pregnant Women With Myeloproliferative Neoplasms – Hematology Advisor

Hematology Advisor shared a post on LinkedIn:

“New research from ASCO26 shows higher maternal mortality rates for pregnant women diagnosed with myeloproliferative neoplasms MPNs.

The physiological hypercoagulability of pregnancy, compounded by MPN-driven erythrocytosis or thrombocytosis, severely amplifies the risk of life-threatening events across all trimesters and the postpartum window.

Key Areas for Clinical Vigilance:

  • Thrombotic and Vascular Burden: Marked increase in deep vein thrombosis, pulmonary embolism, splanchnic vein thrombosis, and stroke.
  • Obstetric Pathologies: Higher baseline incidence of placental insufficiency, preeclampsia, early miscarriage, and stillbirth.
  • Hemostatic Paradox: Concurrent elevation in bleeding risks, notably postpartum hemorrhage, requiring careful titration of antiplatelet or anticoagulant agents.

Read the article here.”

Hematology Advisor

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