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Beata Blazkova: Would You Treat a 0.03 Difference as Decisive in Embryo Selection?
Beata Blazkova/LinkedIn
Feb 24, 2026, 00:57

Beata Blazkova: Would You Treat a 0.03 Difference as Decisive in Embryo Selection?

Beata Blazkova, ESHRE-Certified Senior Clinical Embryologist at Prague Fertility Centre, shared a post on LinkedIn:

“The 0.03 Difference: When AI Scores Look Decisive

Two blastocysts.
Same patient. Same cycle.

An AI system estimates implantation probability:

Embryo A: 0.71
Embryo B: 0.68

A three-percentage-point difference.

The model ranks Embryo A first.

But is that difference clinically meaningful?

Statistically, the algorithm distinguishes between them.
Clinically, the gap may fall within:

  • model uncertainty
  • confidence interval overlap
  • biological variability
  • limits of training data

Yet numbers carry psychological weight.

0.71 feels safer than 0.68.
Even if the difference may not translate into a different real-world outcome.

This is where statistical significance and clinical significance diverge.

And this is where patient communication becomes critical.

Do we present the higher number as a clear advantage?
Or do we explain that a 0.03 gap may not change the biological reality?

AI generates probabilities.
It does not generate certainty.

Precision can create the illusion of control in a system that remains deeply biological and unpredictable.

So here is the real question:

Would you treat a 0.03 difference as decisive in embryo selection?”

Beata Blazkova: Would You Treat a 0.03 Difference as Decisive in Embryo Selection?

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