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Aumatma Simmons: Pre-Menstrual Spotting – A Clinically Significant Cycle Red Flag

Aumatma Simmons/LinkedIn

Aug 20, 2026, 14:04

Aumatma Simmons: Pre-Menstrual Spotting – A Clinically Significant Cycle Red Flag

Aumatma Simmons, Co-Founder and Chief Fertility Officer at Madre Fertility, shared on LinkedIn:

“Pre-Menstrual Spotting: A Clinically Significant Cycle Red Flag.

Brown spotting occurring 3-5 days before menstruation represents a clinically significant finding often dismissed as normal variation, warranting further investigation.

Clinical Associations:

Pre-menstrual spotting typically indicates:

Insufficient progesterone production
Luteal phase defect
Potential thyroid dysfunction

Evidence Base:

Research published in the Journal of Clinical Endocrinology and Metabolism demonstrated that women with luteal phase defects exhibited significantly lower progesterone levels and higher rates of pre-menstrual spotting compared to women with normal fertility parameters.

Additionally, a 2019 study in Fertility and Sterility found that women with thyroid dysfunction were 2.3 times more likely to experience pre-menstrual spotting.

Clinical Implication: This symptom, while common, should prompt evaluation of luteal phase progesterone levels and comprehensive thyroid function rather than dismissal as normal cycle variation.”

Aumatma Simmons: Pre-Menstrual Spotting – A Clinically Significant Cycle Red Flag