Manuel Spitschan/researchgate.net
Aug 23, 2026, 15:22
Manuel Spitschan: The Menstrual Cycle is Biology, Not Noise
Manuel Spitschan, Academic Program Director (APD) for Health Science at the Technical University of Munich, shared on LinkedIn:
” ‘The menstrual cycle is biology, not noise.’
Yesterday at the Swiss Society for Sleep Research, Sleep Medicine and Chronobiology (SSSSC) meeting in Zürich, I gave a talk titled ‘Sex as a biological variable in circadian and neuroendocrine responses to light’.
The four main messages from my talk were:
- Sex matters for circadian and neuroendocrine responses to light, yet the evidence base remains substantially sex-biased, with female participants historically underrepresented or excluded.
- Differences begin with exposure itself. Female participants may receive systematically different amounts and timing of light, including substantially lower morning light exposure.
- Female physiology should be studied, not controlled away. Menstrual-cycle and hormonal variation are biologically meaningful dimensions that may reveal mechanisms of light sensitivity.
- Better evidence requires better study design, including balanced recruitment, explicit sex-stratified analyses, appropriate measurement of hormonal state, preregistration, and Registered Reports.
Thank you to the organizers and co-speakers – Esther Irene Schwarz, Sarah Schoch and Christian Cajochen – and everyone at SSSSC for the thoughtful discussion. And a huge thanks to my co-chair Daniela Noain!”

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