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Robert Brennan: Non-Invasive Metabolomic Test for Embryo Selection

Robert Brennan/LinkedIn

Oct 1, 2025, 10:36

Robert Brennan: Non-Invasive Metabolomic Test for Embryo Selection

Robert Brennan, Chief Executive Officer at Embryomic, shared a post by Embryomic on LinkedIn:

“Sharing Week 2 of our five-part preprint series on PMT-BC, Embryomic’s non-invasive metabolomic test for embryo selection.
This paper asks a key question in IVF: what defines success — implantation or viability?
By analysing spent culture media, PMT-BC helps distinguish these outcomes and complements morphology and PGT-A to improve viable pregnancy rates.”

Quoting Embryomic’s post:

“Week 2 of our five-part PMT-BC preprint series is now live.

This release focuses on one of the most important questions in IVF: how do we define success in embryo selection – implantation or viability?
Implantation: whether the embryo attaches to the endometrium
Viability: whether implantation leads to a sustained pregnancy
By analysing metabolomic profiles from spent culture media, PMT-BC helps to distinguish these outcomes, providing a more clinically relevant measure of embryo competence.
This work lays the foundation for PMT-BC to complement morphology and PGT-A, supporting clearer, evidence-based decisions for embryo transfer.

Read the Week 2 preprint here.”