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Rethinking the Biological Clock – How Age Impacts Eggs and Sperm
Nov 2, 2025, 03:03

Rethinking the Biological Clock – How Age Impacts Eggs and Sperm

Ashok Yadav, Biology faculty at Apex Academy, shared a post on LinkedIn:

“A groundbreaking 2025 study published in Science Advances has revealed that while women experience a decline in the number of eggs as they age, the quality of those eggs at the DNA level remains surprisingly stable. In contrast, men’s sperm accumulates genetic mutations over time, making older fathers more likely to pass on DNA errors that can contribute to developmental and neurological conditions in their children.

Researchers found that these sperm mutations increase steadily with age, particularly after 40, while eggs showed minimal DNA damage accumulation. This challenges decades of assumptions about female fertility and aging – and flips the traditional ‘biological clock‘ narrative on its head.

The implications are significant: men’s age can influence conception success, pregnancy outcomes, and long-term child health just as much as women’s.

In essence, time affects both sexes – just in very different ways.”

Sperm

Stay updated on all scientific advances in the field of fertility with Fertility News.

Ashok Yadav biological clock DNA Fertility Fertility News genetic mutation men’s sperm pregnancy Science Advances sperm
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