Adenomyosis Doesn’t Look the Same at 16, 46, or 60 – The Lancet Obstetrics, Gynaecology, and Women’s Health
The Lancet Obstetrics, Gynaecology, and Women’s Health shared a post on LinkedIn about a paper by Silvia Vannuccini et al.:
“Adenomyosis doesn’t look the same at 16 as it does at 46, or at 60.
Paper 1 of our Adenomyosis Series, published in The Lancet Obstetrics, Gynaecology, and Women’s Health, reframes Adenomyosis as a life-course condition.
Silvia Vannuccini, Francesco La Torre, and Felice Petraglia trace how:
- symptoms, imaging phenotypes, comorbidities, and treatment goals change over time from adolescence and early reproductive life when pain predominates,
- later reproductive life and perimenopause during which time abnormal bleeding, anaemia, and endometrial pathologies become more prominent,
- after menopause when adenomyosis can persist, often with a more fibrotic phenotype.
Other key messages include:
- Diagnosis should not rely on imaging alone. Combine it with history, symptoms, and assessment of coexisting disorders.
- Iron deficiency is common and often under-recognised in heavy menstrual bleeding. Iron replacement should be part of management.
- Treatment should be individualised and adapted over time. High-quality trials and dedicated guidelines are still needed.”
Title: Tailored management of abnormal uterine bleeding and pain in adenomyosis across the life course.
Authors: Silvia Vannuccini, Francesco La Torre, Felice Petraglia.
You can read the Full Article in The Lancet Obstetrics, Gynaecology, and Women’s Health.
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