Renee White: Meaningful Data on the Best IVF Stimulation Protocol for Young Patients with Poor Prognosis
Renee White, Founder and CEO at Fill Your Cup, shared on LinkedIn about a paper by Nan Jia et al. published in the Journal of Ovarian Research:
“The debate over which IVF stimulation protocol works best for young patients with poor prognosis has gone on for years. A new study just gave us some real data to work with.
Almost 5,000 IVF cycles were followed to compare a longer, pause-first protocol against a shorter one in women under 35 with low ovarian reserve. The longer protocol was associated with meaningfully higher clinical pregnancy and live birth rates, along with fewer cancelled cycles.
Low ovarian reserve shows up far more often in the 20s and early 30s than most people expect, and it doesn’t get nearly enough conversation in the fertility space.
This is a retrospective study, not a randomised trial, so it’s not the final word. But it’s a meaningful data point worth bringing into conversations with patients navigating this exact decision.
Follow for more evidence-based breakdowns on fertility and reproductive health.”
Title: Comparing the clinical pregnancy outcomes of fresh embryo transfer in young patients with poor prognosis using different ovarian stimulation protocols
Authors: Nan Jia, Ruolei Wang, Qiuyuan Li, Haoying Hao, Siyue Xu, Lei Jin, Yundong Mao, Juanzi Shi, Cuilian Zhang, Xiaoyan Liang, Shaodi Zhang
You can read the Full Article in the Journal of Ovarian Research.

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