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Sean Lauber: How Many Euploid Embryos Do You Need to Have a Baby?
Sean Lauber/LinkedIn
Sep 4, 2026, 16:37

Sean Lauber: How Many Euploid Embryos Do You Need to Have a Baby?

Sean Lauber, Founder of Remembryo, shared on LinkedIn:

“How many euploid embryos do you need to have a baby?

Large studies of patients transferring euploid embryos one at a time suggest that the overall chance of having at least one live birth is about:

  • 1 euploid: 63-65%
  • 2 euploids: 83-84%
  • 3 euploids: 92-93%
  • 4 euploids: 96%
  • 5 euploids: 98%

This helps explain the common rule of thumb that it takes about three euploid embryos per baby.

But that’s not exactly what the evidence shows.

Many patients won’t need three. About 63-65% had a live birth after their first transfer, and these numbers are population averages, not predictions for an individual patient.

These studies estimated the chance of at least one live birth across groups of patients, but they can’t predict how many embryos an individual patient will actually need.

Some patients will have a live birth after their first transfer, while others may need several.

And if the first euploid transfer fails, the next embryo can still have a good chance of success. In the largest study, live birth rates remained around 50-58% per transfer from the second through fifth attempts.

Euploid embryos aren’t all equivalent either. Developmental day, embryo grade, age, and other patient and clinic factors may affect the chance of success.

I’ve put together a new Evidence Guide that includes the evidence behind these estimates, what happens after failed transfers, factors that may change success, important evidence gaps, and interactive calculators for subscribers.

Check out more details on Remembryo.

Get a free weekly summary of the latest IVF research.”

Sean Lauber: How Many Euploid Embryos Do You Need to Have a Baby?

Other articles featuring Sean Lauber on Fertility News.

Cumulative Live Birth embryo development Embryo Grading embryo transfer Euploid Embryo Transfer Euploid Embryos Failed Embryo Transfer Fertility Fertility News fertility research in vitro fertilization IVF IVF Success Rates live birth OBGYN reproductive health Reproductive Medicine Sean Lauber Women’s Health
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